Aartjan Velthuis

First name

Aartjan

Middle name

J W Te

Last name

Velthuis

Pitre, Emmanuelle, Karishma Bisht, Kaleigh A Remick, Amir Ghorbani, Jonathan Yewdell, Elizaveta Elshina, and Aartjan J W Te Velthuis. (2025) 2025. “A Two-Step Mechanism for RIG-I Activation by Influenza Virus MvRNAs.”. Science Advances 11 (32): eadw8034. doi:10.1126/sciadv.adw8034.

Reference Link
Lamb, Caitlin H, Aartjan J W Te Velthuis, Cameron Myhrvold, and Benjamin Nilsson-Payant. (2025) 2025. “Amplification-Free Detection of Zoonotic Viruses Using Cas13 and Multiple CRISPR RNAs.”. Journal of General Virology. doi:10.1099/jgv.0.002169.

Reference Link
Oade, Michael S, and Aartjan J W Te Velthuis. (2025) 2025. “Molecular Insights into Noncanonical Influenza Virus Replication and Transcription.”. Annual Review of Virology. doi:10.1146/annurev-virology-092623-101331.

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Swaminath, Sharmada, Marisa Mendes, Yipeng Zhang, Kaleigh A Remick, Isabel Mejia, Melissa Güereca, Aartjan J W Te Velthuis, and Alistair B Russell. (2025) 2025. “Analysis of NS2-Dependent Effects on Influenza PB1 Segment Extends Replication Requirements Beyond the Canonical Promoter.”. Nature Communications 16 (1): 1875. doi:10.1038/s41467-025-57092-2.

Reference Link
Lamb, Caitlin H, Emmanuelle M Pitré, Sean Ajufo, Charlotte Rigby V, Karishma Bisht, Michael S Oade, Hamid Jalal, Cameron Myhrvold, and Aartjan J W Te Velthuis. (2024) 2024. “Quantification of Influenza Virus Mini Viral RNAs Using Cas13.”. RNA (New York, N.Y.) 31 (1): 126-38. doi:10.1261/rna.080174.124.

Reference Link
Teo, Qi, Yiquan Wang, Huibin Lv, Michael S Oade, Kevin Mao, Timothy Tan, Yang Huan, et al. (2025) 2025. “Probing the Functional Constraints of Influenza A Virus NEP by Deep Mutational Scanning.”. Cell Reports 44 (1): 115196. doi:10.1016/j.celrep.2024.115196.

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Elshina, Elizaveta, Emmanuelle Pitre, Marisa Mendes, Brandon Schweibenz, Hollie French, Ji Park, Wei Wang, Joseph Marcotrigiano, Alistair B Russell, and Aartjan J W Te Velthuis. (2024) 2024. “Influenza A Virus Transcription Generates Capped CRNAs That Activate RIG-I.”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.11.12.623191.

Reference Link
Sabsay, Kimberly R, and Aartjan J W Te Velthuis. (2024) 2024. “Using Structure Prediction of Negative Sense RNA Virus Nucleoproteins to Assess Evolutionary Relationships.”. Virus Evolution 10 (1): veae058. doi:10.1093/ve/veae058.

Reference Link
Funk, Mathis, Monique I Spronken, Theo M Bestebroer, Anja C M de Bruin, Alexander P Gultyaev, Ron A M Fouchier, Aartjan J W Te Velthuis, and Mathilde Richard. (2024) 2024. “Transient RNA Structures Underlie Highly Pathogenic Avian Influenza Virus Genesis.”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.01.11.574333.

Reference Link
Li, Yuan, Sarah Arcos, Kimberly R Sabsay, Aartjan J W Te Velthuis, and Adam S Lauring. (2023) 2023. “Deep Mutational Scanning Reveals the Functional Constraints and Evolutionary Potential of the Influenza A Virus PB1 Protein.”. Journal of Virology 97 (11): e0132923. doi:10.1128/jvi.01329-23.

Reference Link
Sabsay, Kimberly R, and Aartjan J W Te Velthuis. (2023) 2023. “Negative and Ambisense RNA Virus Ribonucleocapsids: More Than Protective Armor.”. Microbiology and Molecular Biology Reviews : MMBR 87 (4): e0008223. doi:10.1128/mmbr.00082-23.

Reference Link
Rigby, Charlotte, V, Kimberly R Sabsay, Karishma Bisht, Dirk Eggink, Hamid Jalal, and Aartjan J W Te Velthuis. (2023) 2023. “Evolution Of transient RNA Structure-RNA Polymerase Interactions In respiratory RNA Virus Genomes.”. Virus Evolution 9 (2): vead056. doi:10.1093/ve/vead056.

Reference Link
Vigeveno, René M, Alvin X Han, Robert P de Vries, Edyth Parker, Karen de Haan, Sarah van Leeuwen, Katina D Hulme, et al. (2024) 2024. “Long-Term Evolution of Human Seasonal Influenza Virus A(H3N2) Is Associated With an Increase in Polymerase Complex Activity.”. Virus Evolution 10 (1): veae030. doi:10.1093/ve/veae030.

Reference Link
Holubovska, Olga, Pavlo Babich, Alla Mironenko, Jens Milde, Yuriy Lebed, Holger Stammer, Lutz Mueller, Aartjan J W Te Velthuis, Victor Margitich, and Andrew Goy. (2024) 2024. “RNA Polymerase Inhibitor Enisamium for Treatment of Moderate COVID-19 Patients: A Randomized, Placebo-Controlled, Multicenter, Double-Blind Phase 3 Clinical Trial.”. Advances in Respiratory Medicine 92 (3): 202-17. doi:10.3390/arm92030021.

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Park, Sang Woo, Irini Daskalaki, Robin M Izzo, Irina Aranovich, Aartjan J W Te Velthuis, Daniel A Notterman, Jessica E Metcalf, and Bryan T Grenfell. (2023) 2023. “Relative Role of Community Transmission and Campus Contagion in Driving the Spread of SARS-CoV-2: Lessons from Princeton University.”. PNAS Nexus 2 (7): pgad201. doi:10.1093/pnasnexus/pgad201.

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Zhao, Nan, Jessica Sook Yuin Ho, Fanye Meng, Simin Zheng, Andrew P Kurland, Lu Tian, Martha Rea-Moreno, et al. (2023) 2023. “Generation of Host-Directed and Virus-Specific Antivirals Using Targeted Protein Degradation Promoted by Small Molecules and Viral RNA Mimics.”. Cell Host & Microbe. doi:10.1016/j.chom.2023.05.030.

Reference Link
Arcos, Sarah, Alvin X Han, Aartjan J W Te Velthuis, Colin A Russell, and Adam S Lauring. (2023) 2023. “Mutual Information Networks Reveal Evolutionary Relationships Within the Influenza A Virus Polymerase.”. Virus Evolution 9 (1): vead037. doi:10.1093/ve/vead037.

Reference Link
Siegers, Jurre Y, Lucas Ferreri, Dirk Eggink, Edwin J B Veldhuis Kroeze, Aartjan J W Te Velthuis, Marco van de Bildt, Lonneke Leijten, et al. (2023) 2023. “Evolution of Highly Pathogenic H5N1 Influenza A Virus in the Central Nervous System of Ferrets.”. PLoS Pathogens 19 (3): e1011214. doi:10.1371/journal.ppat.1011214.

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